Transient rest restores functionality in exhausted CAR-T cells through epigenetic remodeling

CAR T Cell Immunotherapy Beyond Haematological Malignancy

Stem-like memory T cells are generated during hollow fiber perfusion-based expansion and enriched after cryopreservation in an automated modular cell therapy manufacturing process - Cytotherapy

IJMS, Free Full-Text

Transient mTOR inhibition rescues 4-1BB CAR-Tregs from tonic signal-induced dysfunction

GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas

Adapter CAR T cells to counteract T-cell exhaustion and enable flexible targeting in AML

JCI - Targeting memory T cell metabolism to improve immunity

Mechanisms of CAR T cell exhaustion and current counteraction strategies. - Abstract - Europe PMC

Steering CAR T cell epigenetic programs by tweaking manufacturing protocol - ScienceDirect

T-cell engineering strategies for tumors with low antigen density, and T- cell survival in the immunosuppressive tumor microenvironment of relapsed/refractory diffuse large B-cell lymphoma – ScienceOpen

Rewiring mitochondrial metabolism to counteract exhaustion of CAR-T cells. - Abstract - Europe PMC

Stem-like memory T cells are generated during hollow fiber perfusion-based expansion and enriched after cryopreservation in an automated modular cell therapy manufacturing process - Cytotherapy